中国实用内科杂志2012，Vol.32Issue(6)：419-422,4.
持续性肾脏替代治疗抗凝技术的应用
The current state and prospect of continuous renal replacement treatment anticoagulation technique
管向东 1孙冠青 1陈娟1
作者信息
- 1. 中山大学附属第一医院重症医学科,广州510080
- 折叠
摘要
Abstract
Continuous renal replacement treatment (CRRT) is a common organ function support ive technique in the field of Critical Care Medicine. Since sepsis patients are always combined with hemodynamic instability and coagulation dysfunction , anticoagulation therapy has been an indispensable component part in CRRT for sepsis patients. Anticoagulation therapy enables to slow or reduce the clottings in pipeline and/or filter so as to prolong its life,improve the efficacy of CRRT treatment, and reduce the loss of blood components and thrombosis under pathological state. So far,the common CRRT anticoagulation drugs include heparin,antithrombin,low molecular weight heparin (LMWH) and/or hyparinoids from animal organs, II factor antagonists, nafamostat, sodium citrate and antiplatelet agents. Coagulation function should be regularly monitored in the process of CRRT anticoagulation treatment. Under the circumstance of anticoagulation taboo, heparin-saline priming, predilution and hydrophilic filter can be used to reduce the clottings in pipeline and/or filter.关键词
持续性肾脏替代治疗/脓毒症/凝血功能障碍/抗凝治疗Key words
continuous renal replacement treatment/sepsis/coagulation dysfunction/anticoagulation分类
医药卫生引用本文复制引用
管向东,孙冠青,陈娟..持续性肾脏替代治疗抗凝技术的应用[J].中国实用内科杂志,2012,32(6):419-422,4.
