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猪伪狂犬病病毒SL株TK基因的克隆与生物信息学分析

张士强 易悦 徐志文 朱玲

中国畜牧兽医2012,Vol.39Issue(6):26-30,5.
中国畜牧兽医2012,Vol.39Issue(6):26-30,5.

猪伪狂犬病病毒SL株TK基因的克隆与生物信息学分析

Bioinformatics Analysis of TK Gene of Pseudorabies Virus SL Strain from Pigs

张士强 1易悦 1徐志文 1朱玲1

作者信息

  • 1. 四川农业大学动物医学院,四川雅安625014
  • 折叠

摘要

Abstract

TK gene of pseudorabies virus SL strain was cloned. Based on the sequence, the homology, phylogeny tree, co-don bias, ammo acid structure, hydrophilic and hydrophobicity, transmembrane region and signal peptide were analyzed. The results showed that TK gene was successfully cloned and it consisted 963 nucleotides encoding a protein of 320 amino acids. The TK gene shared over 99. 3% homology with that of the other PRV strains. PRV TK was predicted to not have the trans-membrane region and signal peptide, and not be inside of virus envelope.

关键词

伪狂犬病病毒/TK基因/生物信息学分析

Key words

pseudorabies virusiTK gene/bioinformatics analysis

分类

生物科学

引用本文复制引用

张士强,易悦,徐志文,朱玲..猪伪狂犬病病毒SL株TK基因的克隆与生物信息学分析[J].中国畜牧兽医,2012,39(6):26-30,5.

基金项目

科技部国家科技支撑计划(2006BAD06A18) (2006BAD06A18)

教育部长江学者和创新团队发展计划项目(IRT0848). (IRT0848)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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