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DNA甲基化及其生物学功能OA北大核心CSTPCD

DNA Methylation and its Biological Functions

中文摘要英文摘要

DNA甲基化是一种主要的表观遗传修饰,是调节基因表达的重要手段.作者在介绍了DNA甲基化机制、DNA甲基化的模式、DNA甲基化特点的基础上,重点论述了DNA甲基化发育分化、X染色体失活、基因组印记和杂种优势等方面的作用.

DNA methylation is a major epigenetic modification of genome and plays crucial role in regulation of gene expression. The mechanism, mode and characteristic of DNA methylation were introduced. And the role of DNA methylation in development and differentiation, X chromosome inactivation, gemomic imprinting and heterosis were discussed.

沈秀平;林月霞;徐琪

上海交通大学农业与生物学院,上海200240上海市农业科技服务中心,上海200335上海市农业科学院,上海201106

生物科学

DNA甲基化甲基转移酶基因组印记杂种优势

DNA methylation methyltransferase genomic imprinting heterosis

《中国畜牧兽医》 2012 (6)

83-86,4

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