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肠出血性大肠杆菌Ⅲ型分泌系统调控因素的研究进展

魏波 刘明强 呼和巴特尔

中国畜牧兽医2012,Vol.39Issue(6):161-164,4.
中国畜牧兽医2012,Vol.39Issue(6):161-164,4.

肠出血性大肠杆菌Ⅲ型分泌系统调控因素的研究进展

Development of Regulation Factor of Type Ⅲ Secretion Systems in Enterohaemorrhagic Escherichia coli

魏波 1刘明强 2呼和巴特尔1

作者信息

  • 1. 内蒙古农业大学兽医学院,内蒙古呼和浩特010018
  • 2. 中国人民解放军军事医学科学院,北京100071
  • 折叠

摘要

Abstract

Type Ⅲ secretion systems (T3SS) enable the injection of bacterial proteins through membrane barriers into host cells. This system is required for colonization of their ruminant reservoir hosts by enterohaemorrhagic Escherichia coli (EHEC) and might also be important for the etiology of disease in the incidental human host. T3SS of E. coli inject a cocktail of proteins into epithelial cells that enable bacterial attachment and promotes longer-term colonization in the animal. Here, we review recent progress in our understanding of the regulation of T3SS in EHEC, focusing on the induction and assembly of the T3SS, and the co-ordination of effector protein expression.

关键词

肠出血性大肠杆菌/Ⅲ型分泌系统/效应蛋白

Key words

enterohaemorrhagic Escherichia coli/ type Ⅲ secretion systems/ effector protein

分类

农业科技

引用本文复制引用

魏波,刘明强,呼和巴特尔..肠出血性大肠杆菌Ⅲ型分泌系统调控因素的研究进展[J].中国畜牧兽医,2012,39(6):161-164,4.

基金项目

国家自然基金(C40620610). (C40620610)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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