中国药房2012，Vol.23Issue(22)：2055-2057,3.DOI:10.6039/j.issn.1001-0408.2012.22.13
重症监护病房真菌感染的病原菌分布与耐药性分析
Pathogen Distribution and Drug Resistance of Fungal Infections in Intensive Care Unit
任云 1彭曦 1张永军1
作者信息
- 1. 石河子大学医学院第一附属医院药剂科,新疆石河子832008
- 折叠
摘要
Abstract
OBJECTIVE: To analyz the common bacteria, their pathologic sites and drug resistance of fungal infection in the intensive care unit (ICU), and to provide etiological basis for rational use of antiningal agents. METHODS:Medical records of 660 patients in ICU were investigated in our hospital from 2009 to 2010 retrospectively. The fungal infections species, strains distribution and drug-resistance were analyzed statistically. RESULTS: Fungal infections were found in 98 cases (14.8%). The respiratory tract infection accounted for 50.0% and urinary tract infection for 43.4% in the 98 cases. A total of 106 strains of fungi were isolated, in which Candida albicans, C. tropicalis and C. glabrata accounted for 51.9% , 34.0% and 9.4%. To fluconazole, itracon-azole, voriconazole there was a high resistance (resistance rate≥47.2% ); to amphotericin B, 5-fluorouracil, nystatin they were sensitive (sensitivity rate ≥81.8%). CONCLUSION: We should pay attention to the cultivation of fungi identification and susceptibility test, actively carry on fungal drug resistance monitoring, and pay close attention to changes in fungal resistance. Make a reasonable choice of antifungal agents to prevent and delay further expansion of drug-resistant strains.关键词
真菌感染/病原茵/耐药性/重症监护病房Key words
Fungal infection/ Pathogen/ Drug resistance/ Intensive care unit
分类
医药卫生引用本文复制引用
任云,彭曦,张永军..重症监护病房真菌感染的病原菌分布与耐药性分析[J].中国药房,2012,23(22):2055-2057,3.
