中国药房2012，Vol.23Issue(23)：2137-2139,3.DOI:10.6039/j.issn.1001-0408.2012.23.10
辛苍鼻舒胶囊中挥发油成分的提取与包合工艺研究
Study on Extraction and Inclusion Technology of Volatile Oils from Xincang Bishu Capsules
李罗清 1黄慧 1田素英2
作者信息
- 1. 惠州市中医医院,广东惠州516001
- 2. 广东药学院中山校区实验中心,广东中山 528458
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the extraction and inclusion technology of volatile oil from Radix Et Rhizoma Asari, Ligusticum chuanxiong, Xanthium sibiricum and Flos Mangnoliae in Xincang bishu capsules. METHODS: The extraction technology was optimized by orthogonal experiment with soaking time, amount of added water, extraction time as factors using the volume of volatile oil as index. The inclusion technology was investigated with ratio of volatile oil to β-cyclodextrin, inclusion temperature and inclusion time as factors using yield ratio of inclusion compound as index. RESULTS: The optimized extraction conditions were: 10-fold water, soaking for 1 h, extracting for 8 h. The optimal inclusion conditions were: applying the saturated aqueous solution method, the proportion of β-cyclodextrin to volatile oil was 6:1, lasting 60 min at 40℃. CONCLUSION: The optimum conditions for extraction and inclusion are reasonable and feasible.关键词
辛苍鼻舒胶囊/挥发油提取/β-环糊精包合/工艺/正交试验Key words
Xincang bishu capsules/ Extraction of volatile oil/ Inclusion with β-cyclodextrin/ technology/ Orthogonal experiment分类
医药卫生引用本文复制引用
李罗清,黄慧,田素英..辛苍鼻舒胶囊中挥发油成分的提取与包合工艺研究[J].中国药房,2012,23(23):2137-2139,3.
