中国药理学通报2012，Vol.28Issue(8)：1042-1045,4.DOI:10.3969/j.issn.1001-1978.2012.08.02
钾离子通道在抑郁症中的作用
Role of potassium channels in major depression disorder
陈春林 1王晓良1
作者信息
- 1. 中国医学科学院-北京协和医学院药物研究所,北京,100050
- 折叠
摘要
Abstract
Major depressive disorder ( MDD ) is a common psychiatric disorder. With the growing social pressure, incidence of this disease has been rising gradually. Early studies have proved that neurotransmitters ( serotonin, noradrenaline etc ) disorder in brain is the key factor of MDD. At present, the close relationship between votage-dependent potassium channel, two pore domain potassium channel and MDD has been discovered. The aim
of this paper is to review the recent progress of research in MDD and potassium channels, and provide new views in the drug development of antidepressant.关键词
抑郁症/钾离子通道/电压依赖性钾通道/钾离子通道阻断剂/双孔钾通道/氟西汀Key words
major depressive disorder/ potasium channels/ votage-dependent potassium channel/ potassium channel block-ers/ two pore domain potassium channel/ fluoxetine分类
医药卫生引用本文复制引用
陈春林,王晓良..钾离子通道在抑郁症中的作用[J].中国药理学通报,2012,28(8):1042-1045,4.
