中国药理学与毒理学杂志2012，Vol.26Issue(2)：251-254,4.DOI:10.3867/j.issn.1000-3002.2012.02.023
应用斑马鱼模型评价纳米粒子毒性机制的研究进展
Progress in application of zebrafish model in evaluation of nanotoxic mechanism
陈亨宇 1付爱玲 2赵宝全1
作者信息
- 1. 西南大学药学院,重庆400715
- 2. 军事医学科学院毒物药物研究所军事毒理学研究室,北京100850
- 折叠
摘要
Abstract
Science in nanometer scale, one of the most important research fields in 21 century. In present, a-chievements that have been made in nanotoxicity are basically based on in vitro systems. However, in vivo study developed tardily. Zebrafish, a kind of mode organism, which has more advantages than others in toxicity assessment, will be used more and more wildly in this field. This review summarized some investigative methods, results of in
vivo nanostructures toxicology and the advantages of the mode organism-zebrafish to provide some help for its
development and the methods being systematism.关键词
纳米粒子/毒理学/斑马鱼Key words
nanoparticles/ toxicology/ zebrafish分类
医药卫生引用本文复制引用
陈亨宇,付爱玲,赵宝全..应用斑马鱼模型评价纳米粒子毒性机制的研究进展[J].中国药理学与毒理学杂志,2012,26(2):251-254,4.
