中国药业2012，Vol.21Issue(10)：57-58,2.
178例儿童肾病综合征免疫抑制剂用药分析
Analysis of Immunosuppressive Agents Application in 178 Cases with Pediatric Nephrotic Syndrome
高茗 1张征 2何旭3
作者信息
- 1. 中国人民解放军南京军区南京总医院药品科,江苏南京210002
- 2. 中国人民解放军南京军区联勤部卫生部药品器材处,江苏南京210016
- 3. 中国人民解放军南京军区总医院儿科,江苏南京210002
- 折叠
摘要
Abstract
Objective To understand the drug use trend of immunosuppressive agents in pediatric nephrotic syndrome and to evaluate the rationality of drug use for promoting the clinical pharmaciststo better participate in pediatric rational drug use. Methods The rational medication PASS software system was adopted to access the medication information of the pediatric patients diagnosed with nephrotic syndrome from July to September 2010. The Clinical Application Guidelines of Gglucocorticosteroid' and the 'Evidence Based Guideline of Common Renal Diseases in Children formulated' by the Ministry of Public Health were used as the evaluation standard. Results The main drug for treating nephrotic syndrome was glucocorticoid, its dosage and course conformed to the requirements. Because the disease is easy to generate glucocorticoid resistance,other immunosuppressants are often used alone or combined with glucocorticoid. The data analysis showed that pediatric immunosuppressant application adopted the individuation treatment according to different stages of the disease. Combination of immunosuppressants also choose drugs affecting different locus. Conclusion From the drug use trend and experience, besides glucocorticoid,tacrolimus and tripterygium glucoeides are common immunosuppressants in pediatric nephrotic syndrome and have become the promising effective ways to treat nephrotic syndrome.关键词
儿童/肾病综合征/免疫抑制剂/用药分析Key words
children/ nephrotic syndrome/ immunosuppressant/ medication analysis分类
医药卫生引用本文复制引用
高茗,张征,何旭..178例儿童肾病综合征免疫抑制剂用药分析[J].中国药业,2012,21(10):57-58,2.
