中国药业2012，Vol.21Issue(14)：20-21,2.
叶绿素铜钠稳定性影响因素研究
Study on Influence Factors of Stability of Sodium Copper Chlorophyll
王修东 1楼飞群 1贾天亮 1易继财1
作者信息
- 1. 杭州前进药业有限公司,浙江,杭州,310023
- 折叠
摘要
Abstract
Objective To study the main factors influencing the stability of sodium copper chlorophyll. Methods The contents of sodium copper chlorophyll was determined by using UV spectrophotometry and the factors influencing the stability of sodium copper chlorophyll were investigated, including the acidic environment, temperature, oxidant and reductant, metal ions, light and moisture content in the chlorophyll sodium copper granules. Results Sodium copper chlorophyll showed obvious decrease of the stability under the acidic environment, especially pH < 4 and good stability under 85 ℃. The degradation of sodium copper chlorophyll was fast when temperature was above 85℃. The stability of sodium copper chlorophyll was affected by the metal ions Mg2+ , Zn2 +, AL3+ as well as oxidant and reductant H2O2 and Na2S2O3,but light had no obvious influence on sodium copper chlorophyll. The high moisture content in the chlorophyll sodium copper granules influenced its stability significantly. Conclusion The stability of sodium copper chlorophyll is easy to be affected by the acidic environment, high temperature, oxidant and reductant, divalent and trivalent metal ions as well as moisture content in the granules used in making tablets.关键词
叶绿素铜钠/含量/稳定性/影响因素Key words
sodium copper chlorophyll/ content/stability/influence factor分类
医药卫生引用本文复制引用
王修东,楼飞群,贾天亮,易继财..叶绿素铜钠稳定性影响因素研究[J].中国药业,2012,21(14):20-21,2.
