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冬凌草甲素对家兔肠平滑肌活动的影响

杨敏 卢静 牟金金 徐珽

中国药业2012,Vol.21Issue(14):26-28,3.
中国药业2012,Vol.21Issue(14):26-28,3.

冬凌草甲素对家兔肠平滑肌活动的影响

Effects of Oridonin on Activities of Rabbit' s Intestinal Smooth Muscle

杨敏 1卢静 2牟金金 1徐珽 1

作者信息

  • 1. 四川大学华西医院药剂科,四川,成都,610041
  • 2. 四川大学华西药学院,四川,成都,610041
  • 折叠

摘要

Abstract

Objective To study the effects of oridonin on the activities of rabbit' s intestinal smooth muscle. Methods With the tensility of intestinal smooth muscle as the index,the changes of contractibility of the intestinal smooth muscle were observed. The effects after administration of the same dosage of the crude extract aqueous solution of oridonin, acetylcholine, atropine sulfate and neostigmine were compared and the effects after administration of different dosages of oridonin were also compared subsequently. Results Obvious effects of oridonin on the contractibility of the intestinal smooth muscle were not observed. Conclusion Intestinal smooth muscle is not sensitive to oridonin,which may provide the reliable basis for the clinical application of oridonin.

关键词

冬凌草甲素/肠平滑肌/肌张力

Key words

oridonin/intestinal smooth muscle/muscular tension

分类

医药卫生

引用本文复制引用

杨敏,卢静,牟金金,徐珽 ..冬凌草甲素对家兔肠平滑肌活动的影响[J].中国药业,2012,21(14):26-28,3.

中国药业

OACSTPCD

1006-4931

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