中国中西医结合影像学杂志2012，Vol.10Issue(2)：97-100,封2,5.DOI:10.3969/j.issn.1672-0512.2012.02.001
针刺合谷穴的静息态脑功能成像研究
Study on acupuncture effect of Hegu point(LI4) with resting-state fMRI
摘要
Abstract
Objective: To explore the acupuncture effect of Hegu point(LI4)on the brain functional connectivity. Methods; Study was carried out on 20 healthy right-handed volunteers. The same sequence of magnetic resonance scans was carried out and 3 resting-state fMRI data before (during, after acupuncture was acquired. Six regions of interest were selected as seed point to analyze the functional connectivity,including posterior cingulate cortex(PCC) ,secondary somatosensory cortex(SII) ,primary somatosensory cortex of face(SIF) .primary somatosensory cortex of hand(SIH) ,primary motor cortex of face(MIF) ,and primary motor cortex of hand(MlH). All fMRI data was analyzed with AFNI program. Intra-group functional connectivity within groups before, during, after acupuncture were calculated, and inter-group functional connectivity between groups (during acupuncture and before acupuncture, after acupuncture and before acupuncture) were also calculated ,and all results were corrected with Monte Carlo method. Results: Intra-group analysis showed that each region of interest had extensive functional connectivity with all the other region of brain. Compared with the functional connectivity before acupuncture,brain functional connectivity during acupuncture showed little significant change. However,functional connectivity after acupuncture for the most of region of interest,including PCC,SIF.SII,MIF,showed that there was significantly strengthened or weakened functional connectivity,except for the SIH and MIH. Conclusion: It was demonstrated that the brain default mode network, the sensorimotor network corresponding to face could be affected by Hegu acupuncture. It was inferred that Hegu point had close connection with face and the delayed effect might play important role in acupuncture.关键词
针刺/穴,合谷/磁共振成像Key words
acupuncture/point LI4(hegu)/magnetic resonance imaging分类
医药卫生引用本文复制引用
赵斌,李落意,杨骏,李传富,徐春生,朱一芳..针刺合谷穴的静息态脑功能成像研究[J].中国中西医结合影像学杂志,2012,10(2):97-100,封2,5.基金项目
国家973计划项目(编号:2010CB530505) （编号:2010CB530505）
安徽省教委重大科研项目(编号:KJ2011ZD05). （编号:KJ2011ZD05）
