中华临床免疫和变态反应杂志2012，Vol.6Issue(2)：103-108,封2,7.
贝赫切特综合征合并冠状动脉性心脏病
Coronary Artery Disease in Behcet' s Disease
朱燕林 1吴庆军 1严晓伟 2唐福林2
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院风湿免疫科,北京100730
- 2. 中国医学科学院 北京协和医学院 北京协和医院心内科,北京100730
- 折叠
摘要
Abstract
Objective To investigate the clinical features, therapy and prognosis of Behcet' s disease ( BD ) complicated with coronary artery disease (CAD). Methods The clinical manifestation, coronary artery angiographic findings, management and prognosis of CAD in BD were analyzed retrospectively. Results Twelve patients of BD complicated with CAD were included, of which eleven patients were male, one female. Acute pressing chest pain was the most common and indicative feature of CAD, usually with corresponding changes in electrocardiogram and elevated cardiac enzymes. Angiographic findings included single or multiple coronary severe stenosis or totally occlusion (6/9), aneurysm (1/9) and insignificant changes (2/9). In addition, recurrent oral ulcerations (12/12), skin lesions (8/12), genital ulcerations (8/12), major vessel involvement (5/12), and positive pathergy test (5/12) were presented. All patients received immunosuppressive agents and coronary secondary prevention therapy. Six patients underwent percutaneous coronary intervention. Conclusion CAD is a rare but life-threatening complication of BD. Coronary stenosis/ occlusion, or aneurysm due to coronary vasculilis might be the most important causes. Management of immunosuppressive agents might improve the prognosis and should be recommended.关键词
贝赫切特综合征/心肌梗死/冠状动脉狭窄/闭塞/动脉瘤Key words
Behcet's disease/ myocantia/ infarction/ coronary stenosis/occlusion/ coronary aneurysm分类
医药卫生引用本文复制引用
朱燕林,吴庆军,严晓伟,唐福林..贝赫切特综合征合并冠状动脉性心脏病[J].中华临床免疫和变态反应杂志,2012,6(2):103-108,封2,7.
