中华临床免疫和变态反应杂志2012，Vol.6Issue(2)：142-146,5.
CD203c分子与变态反应性疾病临床诊断
Role of CD203c in the Pathogenesis of Allergic Diseases and Its Potential Clinical Significance
摘要
Abstract
Ecto-nucleotide pyrophosphatase/phosphodiesterases ( ENPPs) , the members of CD203 family are ecto-enzymes which control signaling through purinoceptors by regulating the metabolism of extracellular nucleotides. Recently, it was found that activated basophil specifically express CD203c, based on flowcytometry-assisted basophil activation test (BAT). Thus CD203c may become an important marker for BAT. Since BAT is believed to be one of the gold standards for diagnosis of allergic diseases, the altered expression of CD203c on the basophil membrane may be of significance for the auxiliary diagnosis of allergic disease.关键词
过敏性疾病/发病机制/诊断/CD203cKey words
allergic disease/ pathogenesis/ diagnosis/ CD203c分类
医药卫生引用本文复制引用
张慧云,钱久荣,沈道明,何韶衡..CD203c分子与变态反应性疾病临床诊断[J].中华临床免疫和变态反应杂志,2012,6(2):142-146,5.基金项目
国家自然科学基金(81060250,30772032,30972714) （81060250,30772032,30972714）
