肿瘤防治研究2012,Vol.39Issue(5):535-537,3.DOI:10.3971/j.issn.1000-8578.2012.05.010
三阴性乳腺癌的临床病理特征及预后分析
Analysis of Chinicopathological Characteristics and Prognosis of Triple Negative Breast Cancer
李星 1龚益平 2熊斌1
作者信息
- 1. 430071武汉,武汉大学中南医院肿瘤科湖北省肿瘤医学临床研究中心 肿瘤生物学行为湖北省重点实验室
- 2. 湖北省肿瘤医院乳腺科
- 折叠
摘要
Abstract
Objective To investigate the clinical pathological characteristics, survival and prognostic factors of patients with triple negative breast cancer. Methods The clinical and pathological data of 560 patients, confirmed as breast cancer in Zhongnan hospital of Wuhan university and hubei cancer hospital from Jan 2004 to Dec 2009,were collected. We analyzed the clinical characteristics , recurrence rate and survival rate of the triple-negative breast cancer(TNBC) patients by comparing the characteristics between the two groups (TNBC and non-TNBC groups). Results Compared with non-TNBC group,the patients of TNBC group were usually young,associated with large masses, high hisralogical grade and lymph node metastasis. There were significant differences in median survival time and the 5-year disease-free rate between TNBC group and non-TNBC group. Tumor mass,lymph node metastasis and menopause were important prognostic factors. Conclusion Triple negative breast cancer is one subtype of breast cancer with poor prognosis.关键词
三阴性乳腺癌/临床病理特征/预后Key words
Triple negative breast cancer /Clinical pathological characteristics/ Prognosis
分类
医药卫生引用本文复制引用
李星,龚益平,熊斌..三阴性乳腺癌的临床病理特征及预后分析[J].肿瘤防治研究,2012,39(5):535-537,3.