中山大学学报（医学科学版）2012，Vol.33Issue(3)：383-386,4.
中重度慢性阻塞性肺疾病患者动态肺过度充气与运能力的关系
Correlation between Dynamic Hyperinflation and Exercise Capacity in Patients with Maderate to Severe Chronic Obstructive Pulmonary Disease
摘要
Abstract
[Objectives]To study the correlation between dynamic hyperinflation (DH) and exercise capacity in patients with chronic obstructive pulmonary disease (COPO). [Methods] Routine lung ventilation function, diffusing function, lung volume and an incremental symptom-limited cycle ergometer exercise were tested in 26 stable COPD patients and 12 healthy controls. Flow-volume curve during tidal breathing and inspiratory capacity (IC) were detected every 1 min at rest and exercise. [Results] The IC (L) was significantly lower in COPD patients at peak exercise than at rest (1.55 ?0.46 vs 2.17 ?0.50,P< 0.001). The AIC was negatively correlated with the peak oxygen consumption in COPD patients (r = -0.422,P< 0.05). The peak IC was negatively correlated with both resting IC (r = -0.743, P < 0.001) and peak VT (r =-0.755, P < 0.001) in COPD patients. [Conclusions] DH might be one of the important factors for exercise intolerance in stable COPD patients during incremental symptom-limited cycle exercise.关键词
肺疾病/慢性阻塞性/动态肺过度充气/运动能力Key words
pulmonary disease,chronic obstructive/dynamic hyperinflation/exercise capacity分类
医药卫生引用本文复制引用
黄旭斌,谢灿茂,严英硕..中重度慢性阻塞性肺疾病患者动态肺过度充气与运能力的关系[J].中山大学学报（医学科学版）,2012,33(3):383-386,4.基金项目
广东省科技计划项目(2009B03081171) （2009B03081171）
广州市科技局科技支撑项目(09A72060166) （09A72060166）
