中国中西医结合杂志2012，Vol.32Issue(6)：751-753,3.
高效抗逆转录病毒治疗艾滋病致血液毒性反应中医证候分析
Analyzing Chinese Medicine Syndromes of Hematotoxicity Reaction Induced by Highly Active Antlretroviral Therapy
摘要
Abstract
Objective To investigate the main features of Chinese medicine (CM) syndromes and differences of hematotoxicity reaction induced by highly active antiretroviral therapy. Methods The information of CM four diagnostic methods was collected by cross-sectional study. Their syndrome features were summed up and their differences were analyzed. Results Of the 216 patients, the main syndromes were qi-blood deficiency syndrome (142 cases, accounting for 65. 7%) and Pi-Shen yang deficiency syndrome (74 cases, accounting for 34.3%). The score of qi-blood deficiency syndrome was obviously lower than that of Pi-Shen yang deficiency syndrome (P < 0.05). The count of CD4+ T cells was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome. There was no statistical difference in the serum viral load between the two groups (P > 0. 05). The quality of life was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome, but with no statistical difference (P>0. 05). Conclusions Qi-blood deficiency syndrome and Pi-Shen yang deficiency syndrome were main syndromes of hematotoxicity reaction induced by HAART. The pathogenic condition of qi-blood deficiency syndrome patients was milder. There was no obvious difference in the quality of life, CD4+ T cells, and the viral loads between two syndromes.关键词
艾滋病/高效抗逆转录病毒疗法/血液毒性反应/中医证候/横断面调查Key words
AIDS/ highly active antiretroviral therapy/ hematotoxicity reaction/ Chinese medicine syndrome/ cross-sectional investigation引用本文复制引用
刘志斌,陈秀敏,金艳涛,郭会军,蒋自强..高效抗逆转录病毒治疗艾滋病致血液毒性反应中医证候分析[J].中国中西医结合杂志,2012,32(6):751-753,3.基金项目
国家科技重大专项“十一五”规划“艾滋病和病毒性肝炎等重大传染病防治”课题项目(No.2008ZX10005-003B) （No.2008ZX10005-003B）
国家中医药管理局中医药重点学科建设项目[ No.国中医药发(2009)30号] （2009）
郑州市科技创新团队建设项目(No.10CXTD140) （No.10CXTD140）
河南省教育科学“十一五”规划2010年课题项目(No.2010-JKGHAZ-0047) （No.2010-JKGHAZ-0047）
