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代谢组学在中药现代化研究中的应用

陈海彬 周红光 俞晓忆 文红梅 吴勉华

中国中西医结合杂志2012,Vol.32Issue(6):831-835,5.
中国中西医结合杂志2012,Vol.32Issue(6):831-835,5.

代谢组学在中药现代化研究中的应用

The Application of Metabonomics In Modem Studies of Chinese Materia Medica

陈海彬 1周红光 2俞晓忆 3文红梅 4吴勉华5

作者信息

  • 1. 南京中医药大学科技处动物实验中心,南京210046
  • 2. 南京中医药大学附属医院肿瘤内科,南京210029
  • 3. 中国药科大学,南京210009
  • 4. 南京中医药大学药学院,南京210046
  • 5. 南京中医药大学校长办公室,南京210046
  • 折叠

摘要

Abstract

Metabonomics, a newly developing subject secondary to genomics, transcriptomics, and pro-teomics, is an important constituent part of systems biology. It is believed to be the final direction of the systems biology. It can be directly applied to understand the physiological and biochemical states by its " metabolome profile" as a whole. Therefore, it can provide a huge amount of information different from those originating from other "omics". In the modernization of Chinese materia medica research, the application of metabonomics methods and technologies has a broad potential for future development. Especially it is of important theoretical significance and application value in holistic efficacies evaluation, active ingredients studies, and safety research of Chinese materia medica.

关键词

代谢组学/中药现代化/中药整体药效评价/中药活性成分/中药安全性

Key words

metabonomics/ modernization of Chinese materia medica/ holistic efficacies evaluation of Chinese materia medica/ active ingredients of Chinese materia medica/ safety of Chinese materia medica

引用本文复制引用

陈海彬,周红光,俞晓忆,文红梅,吴勉华..代谢组学在中药现代化研究中的应用[J].中国中西医结合杂志,2012,32(6):831-835,5.

基金项目

国家自然科学基金资助项目(No.30973742/C190201,81102563) (No.30973742/C190201,81102563)

教育部博士点博导类基金资助项目(No.20113237110001) (No.20113237110001)

江苏高校优势学科建设工程资助项目 ()

中国中西医结合杂志

OA北大核心CSCDCSTPCDMEDLINE

1003-5370

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