中药材2012，Vol.35Issue(2)：182-187,6.
不同产地蟾皮药材的HPLC指纹图谱研究
Study on the HPLC Fingerprint of Toad Skin from Different Regions
段林瑞 1张笑恺 1曹蔚 1谢艳华 1王四旺1
作者信息
- 1. 第四军医大学药学系天然药物学教研室,陕西西安710032
- 折叠
摘要
Abstract
Objective:To study the HPLC fingerprint of toad skin and provide a reliable method for quality control and identification. Methods:It used HPLC for detection and Computer Aided Similarity Evaluation System for processing and analysing HPLC fingerprint . Results :①The common pattern of HPLC fingerprint of toad skin was astablished, 29 peaks were identified as the characteristic fingerprints, in which 9 peaks corresponded to 9 bufogenins. ②Each samples' similarity of relative retention time was all above 0. 99, but the similarity of relative peak areas was low. Conclusion:①The method is accurate and with good reproducibility. The fingerprints can be used for the identification and quality control of toad skin. ②The toad skin from different regions are stable in composition, but the contents of the components are different关键词
蟾皮/不同产地/指纹图谱/高效液相色谱法Key words
Toad skin/Different regions/Fingerprint/HPLC分类
医药卫生引用本文复制引用
段林瑞,张笑恺,曹蔚,谢艳华,王四旺..不同产地蟾皮药材的HPLC指纹图谱研究[J].中药材,2012,35(2):182-187,6.
