中药材2012，Vol.35Issue(2)：300-303,4.
响应曲面法优化无患子油超临界CO2萃取工艺研究及其成分分析
Optimization for Supercritical CO2 Extraction with Response Surface Methodology and Component Analysis of Sapindus mukorossi Oil
吴燕 1肖新玉 2葛发欢3
作者信息
- 1. 中山大学,广东广州510275
- 2. 中药提取分离过程现代化国家工程研究中心,广东广州510240
- 3. 广州中医药大学,广东广州510405
- 折叠
摘要
Abstract
Objective:To study the extraction conditions of Sapindus mukorossi oil by Supercritical CO2 Extraction and identify its components. Methods: Optimized SFE-CO, Extraction by Response Surface Methodology and used GC-MS to analysis Sapindus mukorossi oil compounds. Results: Established the model of an equation for the extraction rate of Sapindus mukorossi oil by Supercritical CO2 Extraction, and the optimal parameters for the Supercritical CO2 Extraction determined by the equation were:the extraction pressure was 30 MPa, temperature was 40 ℃; The separation I pressure was 14 MPa. temperature was 45℃ ; The separation Ⅱ pressure was 6 MPa, temperature was 40℃ ; The extraction time was 60 min and the extraction rate of Sapindus mukorossi oil of 17.58%. 22 main compounds of Sapindus mukorossi oil extracted by supercritical CO2 were identified by GC-MS, unsaturated fatty acids were 86. 59%. Conclusion·This process is reliable, safe and with simple operation, and can be used for the extraction of Sapindus mukorossi oil.关键词
无患子油/超临界CO2萃取/响应曲面法/气质联用Key words
Sapindus mukorossi oil/ Supercritical CO2 Extraction/ Response Surface Methodology/ GC-MS分类
医药卫生引用本文复制引用
吴燕,肖新玉,葛发欢..响应曲面法优化无患子油超临界CO2萃取工艺研究及其成分分析[J].中药材,2012,35(2):300-303,4.
