安徽农业科学Issue(18):9651-9652,2.
杜仲叶提取物对力竭运动及恢复小鼠肝脏和骨骼肌的保护作用
Protective Effects of Extracts from Eucommia ulmiodes Olirer Leaves on Liver and Quadriceps Femoris Tissue of Mice at Exhaustive Exercise and Recovery
摘要
Abstract
[Objective] To study the effects of extracts from Eucommia ulmiodes Olirer leaves (EEUOL) on the levels of SOD, POD and MDA in liver and quadriceps femoris tissue and the levels of AST, ALT and AKP in serum of mice at exhaustive exercise and recovery. [ Method] A total of 72 ICR mice were randomly divided into 6 groups of 12 each; quiet control group (A), quiet EEUOL group (B), exhaustive exercise control group (C) , exhaustive exercise EEUOL group (D), exhaustive exercise recovery control group (E) and exhaustive exercise re-covery EEUOL group ( F). Mice in drug groups were given EEUOL at the dosage of 1.5 g/kg per day for successive 30 days by intragastric. administration, while those in control groups were given distilled water. The exhaustive exercise time of mice in exercise groups was recorded when they swam in the water until exhaustion. After exercise, the blood was immediately sampled from eyeball of mice in groups C and D, the liver and quadriceps femoris tissue were taken from their bodies for later use. Because of mice in groups A and B were not given exercise treatment , the blood was directly sampled from eyeball, and the liver and quadriceps femoris tissue were taken from their bodies. As to groups E and F, the blood was sampled from eyeball after 24 h recovery, and the liver and quadriceps femoris tissue were taken from their bodies. Spec-trophotography was used to measure the contents of MDA, the activity of SOD and POD in liver and quadriceps femoris tissue, and the activity of AST, ALT and AKP in serum of mice at exhaustive exercise and recovery. [ Result] EEUOL could increase the activities of SOD and POD in liver and quadriceps femoris tissue of mice at exhaustion and reduce the levels of MDA in liver and quadriceps femoris tissue of mice at exhaustive exercise and recovery. EEUOL could also reduce the activities of AST, ALT and AKP in serum mice at exhaustive exercise and recovery. [ Conclusion] Extracts from Eucommia idmiodes Olirer leaves have a protective effect on liver and quadriceps femoris tissue of mice at exhaustive exercise, and have an accelerated effect on mice recovery.关键词
杜仲叶提取物/力竭运动及恢复/保护作用Key words
Extracts from Eucommia idmiodes Olirer leaves/Exhaustive exercise and recovery/Protective Effects分类
农业科技引用本文复制引用
刘静..杜仲叶提取物对力竭运动及恢复小鼠肝脏和骨骼肌的保护作用[J].安徽农业科学,2012,(18):9651-9652,2.基金项目
陕西教育学院科研基金项目(11KJ024). (11KJ024)