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Predictive factors of lymph node metastasis in intramucosal poorly differentiated early gastric cancer and their impact on the laparoscopic surgery

Zhibin Huo Shangfeng Luan Hongfeng Nie Yan Qin Shubo Chen Jing Zhang Hua Li Dianchao Wu Tongshan Zhai Shuxia Wang Qihai Xiao Bingge Mu

中德临床肿瘤学杂志(英文版)2012,Vol.11Issue(8):456-459,4.
中德临床肿瘤学杂志(英文版)2012,Vol.11Issue(8):456-459,4.

Predictive factors of lymph node metastasis in intramucosal poorly differentiated early gastric cancer and their impact on the laparoscopic surgery

Predictive factors of lymph node metastasis in intramucosal poorly differentiated early gastric cancer and their impact on the laparoscopic surgery

Zhibin Huo 1Shangfeng Luan 1Hongfeng Nie 1Yan Qin 1Shubo Chen 2Jing Zhang 3Hua Li 1Dianchao Wu 1Tongshan Zhai 1Shuxia Wang 1Qihai Xiao 1Bingge Mu1

作者信息

  • 1. Department of Oncology Surgical, Affiliated Xingtai People Hospital of Hebei Medial University, Xingtai 054001,China
  • 2. Department of Urology Surgical, Affiliated Xingtai People Hospital of Hebei Medial University, Xingtai 054001,China
  • 3. Department of Anatomy, Xingtai Medical College, Xingtai 054001, China
  • 折叠

摘要

Abstract

Objective: The aim of this study was to identify clinicopathological factors predictive of lymph node metastasis (LNM) in intramucosal poorly differentiated early gastric cancer (EGC), and further to expand the possibility of using laparoscopic surgery for the treatment of intramucosal poorly differentiated EGC. Methods: Data from 65 patients with intramucosal poorly differentiated EGC and surgically treated were collected, and the association between the clinicopathological factors and the presence of LNM was retrospectively analyzed by univariate and multivariate logistic regression analyses. Results:Univariate analysis showed that number of tumors, tumor size and lymphatic vessel involvement (LVI) were the significant and independent risk factors for LNM (all P < 0.05). The LNM rates were 5.0%, 18.2% and 66.7%, respectively. There was no LNM in 31 patients without the three risk clinicopathological factors. Conclusion: The number of tumors, tumor size, and LVI are independently associated with the presence of LNM in intramucosal poorly differentiated EGC. Thus, these three risk factors may be used to set as a simple criterion to expand the possibility of using laparoscopic surgery for the treatment of intramucosal poorly differentiated EGC.

关键词

poorly differentiated early gastric cancer/early gastric cancer (EGC)/lymph node metastasis (LNM)/clinicopathological characteristics/laparoscopic surgery

Key words

poorly differentiated early gastric cancer/early gastric cancer (EGC)/lymph node metastasis (LNM)/clinicopathological characteristics/laparoscopic surgery

引用本文复制引用

Zhibin Huo,Shangfeng Luan,Hongfeng Nie,Yan Qin,Shubo Chen ,Jing Zhang ,Hua Li,Dianchao Wu,Tongshan Zhai,Shuxia Wang,Qihai Xiao,Bingge Mu..Predictive factors of lymph node metastasis in intramucosal poorly differentiated early gastric cancer and their impact on the laparoscopic surgery[J].中德临床肿瘤学杂志(英文版),2012,11(8):456-459,4.

基金项目

Supported by a grant from the Science Foundation of Xingtai City (No.20102025-2). (No.20102025-2)

中德临床肿瘤学杂志(英文版)

OACSTPCD

2095-9621

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