南方医科大学学报2012，Vol.32Issue(6)：882-885,4.DOI:10.3969/j.issn.1673-4254.2012.06.028
钬激光前列腺剜除术和开放前列腺切除术治疗大体积良性前列腺增生的Meta分析
Holmium laser enucleation versus open prostatectomy for large volume benign prostatic hyperplasia: a meta-analysis of the therapeutic effect and safety
摘要
Abstract
Objective To compare holmium laser enucleation (HoLEP) versus open prostatectomy (OP) for large volume benign prostatic hyperplasia.Methods The randomized controlled trials (RCTs) pertaining to HoLEP and OP for management of large volume benign prostatic hyperplasia were retrieved from Medline and Embase.Meta-analysis was performed using Review Manager 5.0 software.Results Three RCTs were included in the analysis.No significant differences were found in IPSS or Qmax between HoLEP and OP (P>0.05).Compared with OP,HoLEP was associated with significantly less blood loss,a shorter catheterization time and a shorter hospital stay,but a longer operating time.HoLEP and OP were similar in terms of urethral stricture,stress incontinence,transfusion requirement and the rate of reintervention.Conclusion HoLEP and OP have similar therapeutic effects in the management of large volume benign prostatic hyperplasia.Although with a longer operating time and less resected tissue,HoLEP causes less blood loss and requires a shorter catheterization time and a shorter hospital stay.HoLEP has a comparable safety to OP in terms of the adverse events.关键词
钬激光前列腺剜除术/开放前列腺切除术/大体积前列腺/疗效和安全性/Meta分析Key words
holmium laser enucleation of the prostate/open prostatectomy/benign prostatic hyperplasia/large volume prostate/meta-analysis分类
医药卫生引用本文复制引用
陈晖,汤平,欧汝彪,邓向荣,谢克基..钬激光前列腺剜除术和开放前列腺切除术治疗大体积良性前列腺增生的Meta分析[J].南方医科大学学报,2012,32(6):882-885,4.基金项目
广东省科技计划项目(2008B030301004) （2008B030301004）
