国际医药卫生导报2012，Vol.18Issue(11)：1611-1613,3.DOI:10.3760/cma.j.issn.1007-1245.2012.11.029
白三烯拮抗剂孟鲁斯特钠联合舒利迭治疗老年哮喘的疗效
Leukotriene antagonist montelukast sodium combined with seretide for senile asthma
摘要
Abstract
Objective To investigate the efficacy of leukotriene antagonist montelukast sodium combined with seretide in the treatment of senile asthma.Methods 62 elderly patients with asthma were randomly divided into two groups,and then received conventional treatment plus inhaled seretide of 250 μ g twice daily ( 31 patients,control group ) or plus the same seretide combined with leukotriene antagonist montelukast sodium of 10 mg per night ( 31 patients,study group ).The efficacy was compared between the two groups.Results After treatment,symptoms were markedly relieved and lung function was significantly improved in both groups ( 90.32％ vs.70.97％ for the total effectiveness rate ) symptom relief and improvement in lung function were more significant in the study group [FEV 1.0:(2.24 ± 0.41) Lvs.( 1.92 ± 0.27) L,FEV1.0％:(0.45 ± 0.11 ) vs.(0.37 ± 0.09),PEF:(4.55 ± 0.12) L/s vs.( 4.03 ± 0.27 ) L/s ; P ＜ 0.05].Conclusions Combination therapy with leukotriene antagonist montelukast sodium and seretide for senile asthma has a better efficacy and is worth being applied clinically.关键词
白三烯拮抗剂/孟鲁斯特钠/舒利迭/哮喘/高龄患者Key words
Leukotriene antagonist/Montelukast/Seretide/Asthma/Elderly patients引用本文复制引用
谭立新,林燕梅,刘绍燕..白三烯拮抗剂孟鲁斯特钠联合舒利迭治疗老年哮喘的疗效[J].国际医药卫生导报,2012,18(11):1611-1613,3.
