中国妇幼健康研究2012，Vol.23Issue(4)：458-460,3.DOI:10.3969/j.issn.1673-5293.2012.04.018
儿童重症肺炎支原体肺炎60例临床分析
Clinical analysis of severe mycoplasma pneumoniae pneumonia in 60 children
摘要
Abstract
Objective To discuss the clinical features of severe mycoplasma pneumoniae pneumonia ( MPP ) in children, application of fiberbrochoscopy, glucocorticoid treatment and their prognosis in children. Methods From June 2009 to June 2011 256 cases were diagnosed with MPP and 60 cases of them were diagnosed were severe MPP. The data including clinical characteristics, fiberbrochoscopic and imaging features, extrapulmonary complications, glucocorticoid treatment and prognosis were collected and analyzed. Results All severe MPP were characterized by continued fever, and chief complaint of persistent fever complicated with cough before effective therapy. The mean fever duration was 11.8 ?. 66d before effective therapy, which was longer than 5. 12 ?. 83d of the non-severe MPP group ( t = 16.41 ,P <0. 01 ). Chest CT revealed that in most of the cases, lung lesions were only in unilateral pulmonary, easily accompanied with moderate to large amount pleural effusion and most of them on the superior lobe of right lung. The fiberbronchoscopy revealed obvious swelling of mucosa congestion in the opening of the bronchus and large amount of white and stiff secretion obstructing the opening of the bronchus. The incidence of extrapulmonary lesion was 80. 0% . Inflammatory markers such as level of serum ferritin, level of C-reactive protein, erythrocyte sedimentation rate and lactic dehydrogenase increased significantly in severe MPP. All cases were treated with glucocorticoid at early stage, and the prognosis of cases with severe MPP was good. Conclusion Cases with severe MPP have serious condition and have a long course of disease. Early diagnosis, early treatment with glucocorticoid and bronchoalveolar lav age ( BAL ) are the keys to a successful recovery from severe MPP. Most of cases have good prognosis without pulmonary sequelae.关键词
肺炎支原体肺炎/重症/儿童/诊断/治疗Key words
mycoplasma pneumoniae pneumonia ( MPP )/ severe case/ children/ diagnosis/ treatment分类
医药卫生引用本文复制引用
张静,李卫国,周纬,殷勇,王薇,张磊,袁姝华..儿童重症肺炎支原体肺炎60例临床分析[J].中国妇幼健康研究,2012,23(4):458-460,3.基金项目
上海浦东新区卫生局科研基金资助项目(No.PW2009D-10) （No.PW2009D-10）
