中国妇幼健康研究2012,Vol.23Issue(4):463-465,3.DOI:10.3969/j.issn.1673-5293.2012.04.020
PCT和CRP测定在新生儿败血症早期诊断中的价值
Value of PCT and CRP determination in early diagnosis of neonatal sepsis
吕菊红 1马红茹 1李文君1
作者信息
- 1. 陕西省宝鸡市中心医院小儿科,陕西,宝鸡,721008
- 折叠
摘要
Abstract
Objective To evaluate the clinical significance of procalcitonin ( PCT ) and C-reactive protein ( CRP ) determination in early diagnosis of neonatal sepsis. Methods Retrospective analysis of serum PCT and CRP in 40 cases of neonatal sepsis ( aged 3-28 days ) and 40 cases of non neonatal sepsis ( aged 3-28 days ) was conducted. Results There were significant differences in PCT positive rate between two groups(x2 =58. 35 ,P <0. 05 ). After anti-infection treatment for one week, there were only 4 cases of positive PCT and the positive rate was 10.0% , which was significantly different from that before treatment(x2=57. 94,P <0. 05 ). There was significant difference in CRP positive rate between two groups (x2 = 28. 03 , P < 0. 05 ). The sensitivity and specificity of PCT were higher than those of CRP. Conclusion The sensitivity and specificity of PCT in two groups are high, and they can be used to determine severity of infection, curative effect and prognosis. PCT is superior to CRP in early diagnosis of neonatal sepsis.关键词
降钙素原/C-反应蛋白/新生儿败血症/早期诊断Key words
procalcitonin ( PCT )/C-reactive protein ( CRP )/neonatal sepsis/early diagnosis分类
医药卫生引用本文复制引用
吕菊红,马红茹,李文君..PCT和CRP测定在新生儿败血症早期诊断中的价值[J].中国妇幼健康研究,2012,23(4):463-465,3.