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口腔癌患者情绪异常与下丘脑-垂体-肾上腺轴的调节障碍

经典 贾燕飞 刘传霞

国际口腔医学杂志2012,Vol.39Issue(5):628-630,3.
国际口腔医学杂志2012,Vol.39Issue(5):628-630,3.DOI:10.3969/j.issn.1673-5749.2012.05.019

口腔癌患者情绪异常与下丘脑-垂体-肾上腺轴的调节障碍

Relationship between the mood disorders of patients with oral cancers and disruptions in hypothalamic-pituitary-adrenal axis

经典 1贾燕飞 2刘传霞3

作者信息

  • 1. 四川大学华西口腔医学院,成都,610041
  • 2. 国家中医药管理局时间生物学实验室,成都中医药大学,成都,610075
  • 3. 四川大学华西口腔医院黏膜科,成都,610041
  • 折叠

摘要

Abstract

Oral cancer is the most common neoplasm of the head and neck. Patients with oral cancer show elevated prevalence rates of mood disorder. Mood disorder is a kind of catalyst' in the development of cancer and the prognosis predictor. Mood disorder in oral cancer may be associated with circadian disruption in hypothalamic-pituitary-adrenal (HPA) axis. Based on this analysis, we recommend that alteration of circadian rhythm of the HPA axis may play a crucial role in biology mechanism of intervention on oral cancer with mood disorder.

关键词

口腔癌/情绪障碍/下丘脑-垂体-肾上腺轴

Key words

oral cancer/ mood disorder/ hypothalamic-pituitary-adrenal axis

分类

医药卫生

引用本文复制引用

经典,贾燕飞,刘传霞..口腔癌患者情绪异常与下丘脑-垂体-肾上腺轴的调节障碍[J].国际口腔医学杂志,2012,39(5):628-630,3.

基金项目

国家自然科学基金资助项目(81173322) (81173322)

四川省科技厅基金资助项目(2010JY0036) (2010JY0036)

国际口腔医学杂志

OACSTPCD

1673-5749

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