国际口腔医学杂志2012,Vol.39Issue(5):628-630,3.DOI:10.3969/j.issn.1673-5749.2012.05.019
口腔癌患者情绪异常与下丘脑-垂体-肾上腺轴的调节障碍
Relationship between the mood disorders of patients with oral cancers and disruptions in hypothalamic-pituitary-adrenal axis
摘要
Abstract
Oral cancer is the most common neoplasm of the head and neck. Patients with oral cancer show elevated prevalence rates of mood disorder. Mood disorder is a kind of catalyst' in the development of cancer and the prognosis predictor. Mood disorder in oral cancer may be associated with circadian disruption in hypothalamic-pituitary-adrenal (HPA) axis. Based on this analysis, we recommend that alteration of circadian rhythm of the HPA axis may play a crucial role in biology mechanism of intervention on oral cancer with mood disorder.关键词
口腔癌/情绪障碍/下丘脑-垂体-肾上腺轴Key words
oral cancer/ mood disorder/ hypothalamic-pituitary-adrenal axis分类
医药卫生引用本文复制引用
经典,贾燕飞,刘传霞..口腔癌患者情绪异常与下丘脑-垂体-肾上腺轴的调节障碍[J].国际口腔医学杂志,2012,39(5):628-630,3.基金项目
国家自然科学基金资助项目(81173322) (81173322)
四川省科技厅基金资助项目(2010JY0036) (2010JY0036)