国际口腔医学杂志2012，Vol.39Issue(5)：697-701,5.DOI:10.3969/j.issn.1673-5749.2012.05.038
低氧条件下骨形态发生蛋白2对骨整合的调控
The regulation of bone morphogenetic protein 2 on osseointegration under hypoxia
摘要
Abstract
Under the condition of hypoxia, bone loss would happen, and bone heal would be delayed, even nonunion, and osseointegration would be delayed after implant surgery. Bone morphogenetic protein (BMP) 2 is the central regulator of osteoblast differentiation and participates in the process of bone and cartilage formation whether it is in an individual or combined way. In this article, the bone reaction, the influence of BMP2 on osteoblast and osteoclast differentiation, as well as the interaction between BMP2 and vascular endothelial growth factor and the mechanism of BMP2 regulation of osseointegration under hypoxia are reviewed.关键词
低氧/骨形态发生蛋白/骨整合Key words
hypoxia/ bone morphogenetic protein/ osseointegration分类
生物科学引用本文复制引用
廖晓妤,李迎春..低氧条件下骨形态发生蛋白2对骨整合的调控[J].国际口腔医学杂志,2012,39(5):697-701,5.基金项目
青海省科学基金资助项目(2010-z-724) （2010-z-724）
