国际病理科学与临床杂志2012,Vol.32Issue(2):145-149,5.DOI:10.3969/j.issn.1672-7347.2012.02.011
神经降压素及其受体1与乳腺癌
Neurotensin and its receptor 1 in breast cancer
摘要
Abstract
Neurotensin is a polypeptide, distributed mainly in the brain and the gastrointestinal tract. It has a wide range of central and peripheral effects. Recent studies indicate that the signal of neurotensin and neurotensin receptor 1 is closely associated with proliferation, anti-apoptosis, invasion, and metastasis of breast cancer. The fact that high expression of neurotensin receptor 1 in breast cancer may provide a great potential to exploit new tumor imaging agents based on neurotensin analogues or neurotensin receptor-targeted therapeutic drugs, which may contribute to the early diagnosis and therapy in breast cancer.关键词
乳腺癌/神经降压素/神经降压素受体1Key words
breast cancer/ neurotensin/ neurotensin receptor 1引用本文复制引用
张同先,牛昀,张巍..神经降压素及其受体1与乳腺癌[J].国际病理科学与临床杂志,2012,32(2):145-149,5.基金项目
国家自然科学基金(30872519) (30872519)