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神经降压素及其受体1与乳腺癌

张同先 牛昀 张巍

国际病理科学与临床杂志2012,Vol.32Issue(2):145-149,5.
国际病理科学与临床杂志2012,Vol.32Issue(2):145-149,5.DOI:10.3969/j.issn.1672-7347.2012.02.011

神经降压素及其受体1与乳腺癌

Neurotensin and its receptor 1 in breast cancer

张同先 1牛昀 1张巍1

作者信息

  • 1. 天津医科大学附属肿瘤医院乳腺病理研究室,天津300060
  • 折叠

摘要

Abstract

Neurotensin is a polypeptide, distributed mainly in the brain and the gastrointestinal tract. It has a wide range of central and peripheral effects. Recent studies indicate that the signal of neurotensin and neurotensin receptor 1 is closely associated with proliferation, anti-apoptosis, invasion, and metastasis of breast cancer. The fact that high expression of neurotensin receptor 1 in breast cancer may provide a great potential to exploit new tumor imaging agents based on neurotensin analogues or neurotensin receptor-targeted therapeutic drugs, which may contribute to the early diagnosis and therapy in breast cancer.

关键词

乳腺癌/神经降压素/神经降压素受体1

Key words

breast cancer/ neurotensin/ neurotensin receptor 1

引用本文复制引用

张同先,牛昀,张巍..神经降压素及其受体1与乳腺癌[J].国际病理科学与临床杂志,2012,32(2):145-149,5.

基金项目

国家自然科学基金(30872519) (30872519)

国际病理科学与临床杂志

OACSTPCD

1673-2588

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