国际病理科学与临床杂志2012，Vol.32Issue(3)：226-230,5.
PI3K-Akt-mTOR信号通路与病毒性心肌炎
PI3K-Akt-mTOR signal pathway andviral myocarditis
摘要
Abstract
The PI3K-Akt-mTOR signal pathway is a key intracellular signal transduction pathway, which plays important roles in cell apoptosis, transcription, translation, metabolism, angiogenesis, and the cell replication cycle. Viral myocarditis, resulting from coxsackjevirus B3, primarily involves the immune response and apoptosis rather than cellular damage by the virus per se. It is a commonly acquired heart disease in children. We elucidate changes in the PI3K.-Akt-mTOR signal pathway in cells infected by coxsackievirus B3 which contribute to the pathogenesis of viral myocarditis.关键词
信号通路/凋亡/病毒性心肌炎Key words
signal pathway/ apoptosis/ viral myocarditis引用本文复制引用
陈志衡..PI3K-Akt-mTOR信号通路与病毒性心肌炎[J].国际病理科学与临床杂志,2012,32(3):226-230,5.基金项目
国家自然科学基金(30973233). （30973233）
