南方农业学报2012，Vol.43Issue(4)：502-505,4.DOI:10.3969/j:issn.2095-1191.2012.04.502
超声提取永思小檗盐酸小檗碱工艺的优化
Optimization of technology conditions for ultrasonic extraction of berberine hydrochloride from Berberis tsienii Ying
摘要
Abstract
[Objective]Optimal technology for extracting berberine hydrochloride from Berberis tsienii Ying was studied to accelerate researches and development on berberine hydrochloride in medical industry. [Method]Berberine hydrochloride was extracted using ethanol solvent by ultrasonic extraction method. Single factor experiment and L9(34) orthogonal design were used to observe effects of ethanol concentration, extraction time, extraction temperature and solvents on berberine hydrochloride extraction. [Result]When 150 times ethanol (45%) was used as solvent to extract berberine hydrochloride at 60℃ for 40 min, extraction efficiency was recorded as highest and the cost was the lowest. [Conclusion]Under the best technology conditions, the average content of berberine hydrochloride attained 11.9633 mg/g concentration indicating that it's viable to use ethanol and ultrasonic method for berberine hydrochloride extraction.关键词
永思小檗/盐酸小檗碱/乙醇/超声提取法Key words
Berberis tsienii Ying/ berberine hydrochloride/ ethanol/ ultrasonic extraction分类
医药卫生引用本文复制引用
王绪英,向红,左经会,林长松,杨再超..超声提取永思小檗盐酸小檗碱工艺的优化[J].南方农业学报,2012,43(4):502-505,4.基金项目
贵州省教育厅自然科学基金项目(黔教研[2009]098号) （黔教研[2009]098号）
