河北医学2012，Vol.18Issue(11)：1552-1555,4.DOI:10.3969/j.issn.1006-6233.2012.11.012
坦索罗辛在输尿管下段结石辅助排石中的疗效观察
Observation of the Therapeutic Effect of Tamsulosin on Assisted Expulsion for Treating Lower Ureteral Calculi
洪辉斌 1王乐浩 1王博智 1姚伟1
作者信息
- 1. 广东省汕头市第二人民医院,广东,汕头,515011
- 折叠
摘要
Abstract
Objective: To evaluate the efficacy of tamsulosin in treatment of lower ureteral calculi. Method: A total of 90 consecutive patients with single radiopaque lower ureteral calculi were enrolled in the study. The stone diameter was 0. 4 — 1. 0cm and patients were 21-72 years. All patients were diveded into two groups! 45 cases in each group ). The control group were treated with lavoofloxacin ( 0. 2g bid ) and chi-nese medicine Paishi Decoction ( ldose qd ). The tamsulosin group received the same medicines in the control group plus tamsulosin( 0. 2mg qd ). There's no significant differences in concerning age, gender distribution and maximum stone diameter of two groups. All patients were treated for 10 days and followed up for 15 days. Efficacy was evaluated in term of stone expulsion rate, expulsion time, pain episodes, analgesic use and adverse drug reaction during a week of follow up. Result:The successful stone expulsion rate was 86. 7%( 39/45 ) in the tamsulosin group, which was significantly higher than 57. 8% in the control group ( P< 0. 01 ). Mean expulsive calculi time of the control group and the tamsulosin group were 7. 51 ±2. 34 days,5. 02±1.27 days respectively. There was statistically significant difference ( P<0.05 ). The pain episodes rate and analgesic use rate were 17.8% ( 8/45 ) and 6. 7%( 3/45 ) in the tamsulosin group, which were also significantly lower than those in the control group, which were 42.2%( 19/45 ) and 28.9%( 13/45 ), respectively ( P<0. 05 ). All the patients could tolerate the expulsive calculi therapy and no obvious side effects were found. Conclusion:Tamsulosin can be useful to shorten the duration of the expelling stone, relieves renal colic episode and significantly improve the expulsive calculi rate in the lower ureter. Tamsulosin in the treatment of lower ureteral stones ( 0. 4-1. 0cm in diameter ) is safe.关键词
输尿管下段结石/坦索罗辛Key words
Lower ureteral calculi/Tamsulosin引用本文复制引用
洪辉斌,王乐浩,王博智,姚伟..坦索罗辛在输尿管下段结石辅助排石中的疗效观察[J].河北医学,2012,18(11):1552-1555,4.
