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中药联合干扰素对慢性乙型病毒性肝炎血清HBsAg影响的系统评价

徐学琴 闫国立 孙宁 申杰

中医学报2012,Vol.27Issue(5):648-650,3.
中医学报2012,Vol.27Issue(5):648-650,3.

中药联合干扰素对慢性乙型病毒性肝炎血清HBsAg影响的系统评价

Systematic Review of Influence of Traditional Chinese Medicine Combined with Interferon on Serum HBsAg in Chronic Hepatitis B patients

徐学琴 1闫国立 1孙宁 1申杰1

作者信息

  • 1. 河南中医学院基础医学院,河南郑州 450008
  • 折叠

摘要

Abstract

Objective;To study the influence of Traditional Chinese Medicine! TCM) combined with Interferon(IFN) on Serum HBisAg in Chronic Hepatitis B patients. Methods : Search strategy was established according to the Cochrane systematic review, related data of the articles met inclusion criteria was gathered,and meta analysis was performed using RevMan4. 2. Results:The results of meta -analy-ses showed:for HBsAg seroconversion rate, significant difference was found between the TCM combined with IFN and IFN therapy groups after more than 3 months'therapy, RR and 95%CI were 1.63(1.04,2.55). But no significant difference was found between the TCM and IFN therapy groups,RR and 95%Cl were 1.13(0.47,2.72). Cunclusions:In terms of HBsAg and seroconversion rate,TCM therapy is not superior to IFN therapy,but TCM combined with IFN therapy is superior to IFN therapv.

关键词

乙型病毒性肝炎/中药治疗/干扰素/HBsAg/系统评价

Key words

hepatitis B/ traditional Chinese medicine/ interferon/ HBsAg/ systematic review

分类

医药卫生

引用本文复制引用

徐学琴,闫国立,孙宁,申杰..中药联合干扰素对慢性乙型病毒性肝炎血清HBsAg影响的系统评价[J].中医学报,2012,27(5):648-650,3.

基金项目

河南中医学院苗圃工程项目资助(编号:MP2009-02) (编号:MP2009-02)

中医学报

OACSTPCD

1674-8999

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