河南农业科学2012,Vol.41Issue(4):7-11,5.
抗病毒RNA沉默和病毒拮抗RNA沉默策略研究进展
Antiviral RNA Silencing and Virus Strategies for Silencing Suppression
摘要
Abstract
RNA silencing refers to diverse RNA-directed processes resulting in sequence-specific degradation of target RNA and repression of gene expression either at transcriptional, posttran-scriptional or translational levels. In animals, fungi and plants, RNA silencing represents a mechanism guided by small RNAs against virus infection. Viruses can be inducers and targets of RNA silencing, and have evolved active and passive strategies to counter the cellular antiviral mechanism. This review discusses siRNAs- and miRNAs-mediated antiviral RNA silencing and virus strategies for silencing suppression in order to further clarify the relationship between virus infection and host.关键词
RNA沉默/抗病毒/沉默抑制/小RNAKey words
RNA silencing/ antivirus/ silencing suppression/ small RNAs分类
生物科学引用本文复制引用
施艳,韩卫丽,孙虎,王振跃..抗病毒RNA沉默和病毒拮抗RNA沉默策略研究进展[J].河南农业科学,2012,41(4):7-11,5.基金项目
河南省重点科技攻关项目(072102160007) (072102160007)