摘要
Abstract
Objective To assess the clinical and pathological features of pseudomyxoma peritonei(PMP). Methods Clinical, pathological and follow-up data about 92 PMP patients admitted to our hospital were retrospectively analyzed. The patients were divided into disseminated peritoneal adenomucinosis(DPAM) group(n=49), peritoneal mucinous carcinomatosis(PMCA) group (n=17), and PMCA with intermediate or discordant features (PMC A-I/D) group(n=26). Their survival rate was calculated with the Kaplan-Meier method and related factors for their prognosis were analyzed. Results Twenty-two of the 92 PMP patients died at the mean age of 51.9 years(22-76 years) with a median survival time of 124.0 months and their 3-, 5-, and 10-year survival rate was 74.0%, 67.0% and 49.0%, respectively. Eight patients in DPAM group died with a median survival time of 312.9 months and their 3-, 5-, and 10-year survival rate was 97.0%, 80.0%, and 67.0%, respectively. Six patients in PMCA-I/D group died with a median survival time of 84.0 months and their 3-, 5-, and 10-year survival rate was 80.0%, 67.0%, and 50.0%, respectively. Eight patients in PMCA group died with a median survival time of 31.7 months and their 3- and 5-year survival rate was 65.0% and 28.0%, respectively. The longest follow-up time was 108 months with the best prognosis observed in DPAM group and the poorest prognosis observed in PMCA group(P=0.001). The survival time of the patients, especially those with their age <40 years, was closely related with their age, appendiceal tumor and parenchymal organ involvement. Conclusion PMP should be used as DPAM, PMCA and PMCA-I/D in its pathological diagnosis. Although the pathological morphology of most PMP patients is benign or low malignant, their 10 -year survival rate is rather low. The prognosis of PMP patients, especially those with their age <40 years, is closely related with their age, appendiceal tumor and parenchymal organ involvement.关键词
假黏液瘤/腹膜/病理学/临床/预后Key words
pseudomyxoma peritonei/ peritoneum/ pathological/ clinical/ prognosis分类
医药卫生
