昆明医学院学报2012，Vol.33Issue(5)：66-71,6.
响应面法优化微波提取小香薷籽总黄酮工艺及数学模型研究
Study on Technique Condition of Extracting Total Flavones from Micromeria Barosma(W.W.Smith)Hand.-Mazz.Seed via Response Surface Methodology Optimizing Microwave and Its Mathematical Model
摘要
Abstract
Objective To optimize the extraction technology of total flavonoids from Micromeria barosma (W.W.Smith) Hand.-Mazz. Seed. Methods Based on the single factor analysis, ethanol concentration, presoaking time, solid- liquid ratio to liquid and microwave heating time were chosen as main factors to evaluate the effects on the extraction of the total flavonoids. Results The optimized extraction conditions were as follows: ethanol concentration 97.51%, presoaking time 5.34 min, solid- liquid ratio 1:47.5, microwave heating time 5.76 min. The predictive value of total flavonoid content was 6.67%. Conclusions Under the optimal conditions, the yield of total flavonoids was 6.42%, close to predictive value error =3.7%. The extraction technology is feasible and stable and could be helpful to the factory production and better than orthogonal design.关键词
小香薷籽/总黄酮/微波/响应面法/Box-Behnken设计Key words
Micromeria barosma (W.W.Smith) Hand.-Mazz. seed/ Total flavonoids/ Microwave-assisted extraction/ Response surface method (RSM) / Box- Behnken design分类
轻工业引用本文复制引用
张雪辉,张丽娟,徐芳,王琦,吴少雄,张忠华,高小娇,海寿益,殷建忠..响应面法优化微波提取小香薷籽总黄酮工艺及数学模型研究[J].昆明医学院学报,2012,33(5):66-71,6.基金项目
云南省教育厅科学研究基金资助项目(5Y0281C,08Y0239) （5Y0281C,08Y0239）
昆明医科大学研究生创新基金资助项目(2009J12) （2009J12）
