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联合治疗对妊娠期肝内胆汁淤积症的影响

王秋虹 寸冬云 于恒海 刘锋 胡明道 胡万芹

昆明医学院学报2012,Vol.33Issue(6):92-95,4.
昆明医学院学报2012,Vol.33Issue(6):92-95,4.

联合治疗对妊娠期肝内胆汁淤积症的影响

The Effection of Combined Treatment for Intrahepatic Cholestasis of Pregnancy

王秋虹 1寸冬云 1于恒海 1刘锋 1胡明道 1胡万芹2

作者信息

  • 1. 昆明医科大学第二附属医院肝胆一科,云南,昆明,650101
  • 2. 昆明医科大学第二附属医院产科,云南,昆明,650101
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摘要

Abstract

Objective To investigate the clinical effects of three treatment option for intrahepatic cholestasis of pregnancy (ICP). Methods The patients with intrahepatic cholestasis in pregnancy were randomized to receive signle SAMe, Polyene Phosphatidylcholine or combined treatment for two weeks and the results were compared. Results After combined treatment, there were significant decrease in the degree of the blood level of biochemical parameters such as AST, ALT and TBA (P <0.05). Combined with single treated group, the outcome of pregnancy and the situation of newborns were significantly improved. Conclusion The combined treatment of SAM and Polyene Phosphatidylcholine can obviously improve the outcome of pregnancy and the newborns' quality of life than the single SAM or single Polyene Phosphatidylcholine.

关键词

妊娠期肝内胆汁淤积综合症/腺苷蛋氨酸/多稀磷脂酰胆碱

Key words

Intrahepatic cholestasis of preg nancy/ S-adenosy-L-Methionine/ Polyene Phosphatidylcholine

分类

医药卫生

引用本文复制引用

王秋虹,寸冬云,于恒海,刘锋,胡明道,胡万芹..联合治疗对妊娠期肝内胆汁淤积症的影响[J].昆明医学院学报,2012,33(6):92-95,4.

昆明医学院学报

OACSTPCD

1003-4706

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