昆明医学院学报2012，Vol.33Issue(6)：113-117,5.
新的预后指数模型GPA在肺癌脑转移中的应用分析
Application of New Prognostic Index GPA in Lung Cancer with Brain Metastases
夏耀雄 1李文辉 1王晓莉 1崔建国 1夏群 1杨梅2
作者信息
- 1. 云南省肿瘤医院,昆明医科大学第三附属医院放疗中心,云南,昆明,650118
- 2. 云南省肿瘤医院,昆明医科大学第三附属医院干疗科,云南,昆明,650118
- 折叠
摘要
Abstract
Objective To evaluate the new Graded Prognostic Assessment (GPA) scale in a prospective validation study to compare it with two published prognostic indexes. Methods We reviewed the clinical data of 151 lung cancer patients with brain metastases in our hospital from June 2006 to December 2008.The multivariate analysis was performed with Cox's proportion risk model. Survival analysis was compared with Kaplan-Meier method and log-rank test was used respectively. Statistical significance was defined as P < 0.05. Results The single factor analysis showed that patients' performance status, gender, the number of brain metastases, the absence or presence of extracranial metastases were related to survival period (P < 0.05). The multivariate analysis indicated that patients' performance status and the absence or presence of extracranial metastases were closely related to their prognosis (P < 0.05). Conclusions Our data suggest that the new GPA index is a valid prognostic index as with RPA or BSBM.关键词
肺癌/脑转移瘤/预后因素/预测模型Key words
Lung Cancer/ Brain metastasis/ Prognostic factors/ Predictive index分类
医药卫生引用本文复制引用
夏耀雄,李文辉,王晓莉,崔建国,夏群,杨梅..新的预后指数模型GPA在肺癌脑转移中的应用分析[J].昆明医学院学报,2012,33(6):113-117,5.
