兰州大学学报（医学版）2012，Vol.38Issue(2)：10-14,5.
海氏迪茨菌株中VapA/VapB基因质粒子的表达及临床药敏试验结果分析
Dietzia maris bacterial susceptibility analysis identified by VapA/VapB genotype
摘要
Abstract
Objective To identify the virulence and antigenic structure of strains of Dietzia maris samples collected from Yellow. River precipitate by using VapA/VapB genotype, and to define Dietzia maris's biological characters in clinical samples and to analyze its drug hypersensitivity experimental results. Methods Dietzia maris molecular characteristics and Kirby-Bauer method for susceptibility testing were isolated by using 16S rRNA and the Rhodococcusequi ATCC133701p+ as the standard evaluation. Results The similarity between Dietzia marts and Rhodococcusequi was 80%. Dietzia maris's resistance rate to vancomycin, rifampiciri, ciprofloxacin, ofloxacin, chloramphenicol, ceftriaxone was 0, and the rate to sulfamethoxazole oxazole and penicillin G was 100%. Its resistance rates towards erythromycin, ceftazidime, amikacin and cephalothin were 7.3%, 11.5%, 23.7% and 32.7% respectively. And its resistance rates towards cefazolin, oxacillin and ampicillin were between 65.5% and 91.8%. Conclusion The similarity between Dietz maris and Rhodococcusequi is 80%. Dietz marts is the pathogenic bacteria of some animals, such as horses, pigs and castles. It is also a peculiar pathogenic bacterium of human being. It can cause respiratory infection, urinary tract infection and septicemia. The antibiotics should be used reasonably according to the results of drug sensitivity test in clinic so as to prevent the drug resistance of Dietz maris.关键词
海氏迪茨菌株/VapA/VapB基因质粒子/药敏试验Key words
Dietzia maris/ VapA/VapB genotype/ susceptibility testing分类
生物科学引用本文复制引用
周翔,梁剑平,冉茂胜,陆锡宏,李雪虎,王曙阳..海氏迪茨菌株中VapA/VapB基因质粒子的表达及临床药敏试验结果分析[J].兰州大学学报（医学版）,2012,38(2):10-14,5.基金项目
国家自然科学基金(211105193) （211105193）
中国博士后第五十批面上项目(2011M501484) （2011M501484）
中国科学院近代物理研究所博士后基金(Y161060ZYO) （Y161060ZYO）
