兰州大学学报（医学版）2012，Vol.38Issue(2)：40-42,46,4.
BNP、CRP、TNF-α、IL-6与慢性充血性心力衰竭的诊断和心功能分级相关性
Clinical study of the relationship between BNP, CRP,TNF-α, IL-6 and diagnosis of chronic congestive heart failure and cardiac functional classification
杨晓霞 1杨衍涛 1马莉 1李正东1
作者信息
- 1. 兰州市第一人民医院干部病房,甘肃兰州730050
- 折叠
摘要
Abstract
Objective To observe brain natriuretic peptide (BNP), C-reactive protein (CRP), tumor necrosis factor-α (TNF-a), interleukin-6 (IL-6) changes in patients with chronic congestive heart failure (CHF) to evaluate the relationship between them. Methods Two groups were included in the study. One was the treatment group consisting of 80 patients who met the inclusion criteria and the other was the control group with 60 healthy people. Venous bloods were taken from both group to determine their BNP, CRP, TNF-a and IL-6. Results BNP, CRP, TNF-a and IL-6 were higher in treatment group than in control group with obvious difference (P <0.05). The indexes before and after treatment. In CHF group had statistical significance (P <0.05). Cardiac functional classification groups showed difference before and after treatment {P <0.01}. There were significant difference between the two groups (P <0.01). Conclusion BNP, CRP, TNF-α, IL-6 play an important role in the diagnosis of chronic congestive heart failure and cardiac function. Those indexes can guide clinical diagnosis and help to judge the severity of heart failure. 关键词
慢性充血性心力衰竭/脑尿钠肽/C-反应蛋白/肿瘤坏死因子-α/白介素-6Key words
chronic congestive heart failure/ brain natriuretic peptide/ C-reactive protein/ tumor necrosis factor-a/ interleukin-6分类
医药卫生引用本文复制引用
杨晓霞,杨衍涛,马莉,李正东..BNP、CRP、TNF-α、IL-6与慢性充血性心力衰竭的诊断和心功能分级相关性[J].兰州大学学报（医学版）,2012,38(2):40-42,46,4.
