临床神经外科杂志2012，Vol.9Issue(3)：160-163,166,5.DOI:10.3969/j.issn.1672-7770.2012.03.011
国内尼莫地平治疗自发性蛛网膜下腔出血有效性和安全性的Meta分析
Meta-analysis of efficacy and safety in Nimodipine in the treatment of spontaneous subarachnoid hemorrhage in China
王新军 1文燕 2刘灵慧1
作者信息
- 1. 510632 广州,暨南大学附属第一临床医学院神经外科
- 2. 深圳市龙岗区人民医院
- 折叠
摘要
Abstract
Objective To provide the basis of clinical usage of Nimodopine on spontaneous subarachnoid hemorrhage ( SAH ) through Meta-analysis. Methods Search CJNK1, WangFan Articles and VIP-related clinical trials to process data entry, index analysis, and publication bias. Results Procedure data analysis on heterogeneity test showed no heterogeneity. In the fixed effects model merge, Meta-analysis confirmed that nimodopine can reduce the number of occurrence of CVS afler SAH, and can not increase the rate of rehemorrhage. Dead rate of Nimodipine group was lower than the control group. Begg and Egger assay had prompted the study there was no obvious bias. Conclusion The domestic clinical research evidence shows that Nimodipine is a safe and effective trcatment of spontaneous subarachnoid hemorrhage.关键词
自发性蛛网膜下腔出血/随机对照试验,尼莫地平/脑血管痉挛/Meta分析Key words
spontaneous subarachnoid hemorrhage/ randomized controlled trials/ nimodipine/cerebral vasospasm/ Meta analysis.分类
医药卫生引用本文复制引用
王新军,文燕,刘灵慧..国内尼莫地平治疗自发性蛛网膜下腔出血有效性和安全性的Meta分析[J].临床神经外科杂志,2012,9(3):160-163,166,5.
