临床误诊误治2012,Vol.25Issue(5):75-77,3.DOI:10.3969/j.issn.1002-3429.2012.05.043
卵磷脂络合碘治疗玻璃体积血效果的Meta分析
A Meta-Analysis of Iodized Lecithin in Treating Vitreous Hemorrhage
梁雄姿 1艾明 1江双红 1冯焕焕 1陈阵2
作者信息
- 1. 430060武汉,武汉大学人民医院眼科中心
- 2. 430060武汉,武汉大学人民医院急诊科
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of oral Iodized Lecithin in treating the vitreous hemorrhage. Methods We retrieved the WanFang Medical Databanks, Chinese Biomedical CD Database (CBMdisk) and Cochrane Library during January 2000 and June 2011 for randomized controlled trials about Iodized Lecithin in treating vitreous hemorrhage. We filtered and evaluated the quality of the literature. Meta-analysis was conducted by Rev Man 5.0 software. Results 6 records for indexes included 462 cases and 491 eyes met the criteria for entry. Two in the records were of high quality. Experimental group had better results than control group in general curative effects, OR = 8. 54, 95% Cl ( 5. 14,14. 21). The deflective analytic result of Meta-analysis showed little possibility of deflection. We had 5 papers about adverse reaction in 6 papers, and just 1 paper about slight gastrointestinal discomfort due to Iodized Lecithin. Conclusion The existing clinical evidence shows that oral iodized lecithin in treating the vitreous hemorrhage has better and safer, results but we need further high quality randomized controlled trials to prove it.关键词
玻璃体积血/卵磷脂络合碘/Meta分析Key words
Vitreous hemorrhage/ Iodized lecithin/ Meta-analysis分类
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梁雄姿,艾明,江双红,冯焕焕,陈阵..卵磷脂络合碘治疗玻璃体积血效果的Meta分析[J].临床误诊误治,2012,25(5):75-77,3.