中国临床保健杂志2012，Vol.15Issue(2)：162-164,3.DOI:10.3969/J.issn.1672-6790.2012.02.018
人工虎骨对原发性骨质疏松症患者骨钙素和抗酒石酸酸性磷酸酶5b的影响
Effects of bionic tiger bone on serum BGP and TRACP 5b in patients with primary osteoporosis
祝捷 1董崇周 1徐将 1陈若平 1陈超 1陈燕 1邢学农 1叶山东1
作者信息
- 1. 安徽医科大学附属省立医院、安徽省立医院内分泌科,合肥230001
- 折叠
摘要
Abstract
Objective To investigate the effects of bionic tiger bone (JINTIANGE capsule) on serum bone gamma-carboxyglutamic acid-containing protein (BGP) and tartrate-resistant acid phosphatase 5b (TRACP 5b) in treating primary osteoporosis. Methods Eighty-six postmenopausal women with primary osteoporosis (60. 5 ± 3. 6 years of age) were included and treated orally for 3 months with JINTIANGE capsules (three tablets a time, three times a day). The serum level of BGP was measured by radioimmunoassay before and after treatment. The serum level of TRACP 5b was measured by enzyme-iinked immunosorbent assay. Results The serum level of BGP in patients was significantly increased after 3-month treatment (8.31 ±2. 41 μg/L vs 5.81 ±1.93 (μg/L,P < 0. 05). Furthermore, the serum level of TRACP 5b was significantly decreased after 3 months (2.49 ±0.81 u/L vs 4.26 ± 0.86 u/L,P< 0.05). Conclusion Bionic tiger bone is effective in treating osteoporosis by promoting bone formation and inhibit bone resorption.关键词
骨质疏松/虎骨/人工/骨钙素/酸性磷酸酶Key words
Osteoporosis/Os tigris/artificial/Osteocalcin/Acid phosphatase分类
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祝捷,董崇周,徐将,陈若平,陈超,陈燕,邢学农,叶山东..人工虎骨对原发性骨质疏松症患者骨钙素和抗酒石酸酸性磷酸酶5b的影响[J].中国临床保健杂志,2012,15(2):162-164,3.
