四川医学2012，Vol.33Issue(6)：915-918,4.
极低出生体重儿支气管肺发育不良高危因素分析
Risk factors in bronchopulmonary dysplasia of very-low-birth-weight infants
摘要
Abstract
To study the high-risk factors and prevention for bronchopulmonary dysplasia (BPD) in very-low-birth-weight infants. Methods A retrospective study was conducted at West China Second University Hospital to evaluate the risk factors associated with BPD in very-low-birth-weight. From August 2008 to August 2011, two hundred and forty-one very low birth weight infants were admitted in our NICU. Thirty-one infants with BPD were compared to two hundred and ten ones without BPD in the neonatal and maternal risk factors, treatment and complications. Results The incidence of BPD in the very low birth weight infants was 12.9%. The gestationsl age and birth weight of BPD group were lower than those without BPD, and the rates of infection during pregnancy in BPD group were higher than those without. The incidence of neonatal respiratory distress syndrome (NRDS), pulmonary hemorrhage, intracranial hemorrhages (ICH) , retinopathy of prematurity (ROP) in BPD group were higher than those without (P<0.05). The time of mechanical ventilation and oxygen administration were longer in BPD group (P < 0.001). Logistic regression analysis indicates that gestational age < 30 weeks (OR 5. 033, P< 0.01) and NRDS ( OR 4. 060, P <0.05) significantly increase the risk for BPD. Conclusion Preventing premature labor and infection of pregnant woman,using lung protective strategies of ventilation might be means to prevent BPD in these infants.关键词
极低出生体重儿/支气管肺发育不良/高危因素Key words
very-low-birth-weight infants/ bronchopulmonary dysplasia(bpd)/ risk factors分类
医药卫生引用本文复制引用
杨云帆,石晶,王华,熊英..极低出生体重儿支气管肺发育不良高危因素分析[J].四川医学,2012,33(6):915-918,4.基金项目
卫生部部属(管)医院2010～2012年度临床学科重点项目(编号:92) （管）
