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尿微量蛋白在高胆红素血症新生儿中测定的意义

王译 杜逸亭 徐若梅

四川医学2012,Vol.33Issue(6):948-950,3.
四川医学2012,Vol.33Issue(6):948-950,3.

尿微量蛋白在高胆红素血症新生儿中测定的意义

The function of urinary microdose protein in neonates with hyperbilirubinemia

王译 1杜逸亭 1徐若梅1

作者信息

  • 1. 成都市妇女儿童中心医院新生儿科,四川成都610091
  • 折叠

摘要

Abstract

To investigate the function of urinary microdose protein in neonates with hyperbilirubinemia. Methods The contents of ALB,TRF,α1-MG,β2-MG in urine were detected in 39 neonates with hyperbilirubinemia, the blood bilirubin and creatine were also tested; 35 healthy subjects served as control group. Results The level of urinary nricrodose protein is increasing with bilirubin, α,-MG and β2-MG are higher than normal when bilirubin >220μmol/L; moreover, when bilirubin >256μmol/L, contents of ALB,TRF,α1-MG,β2-MG increased significantly. Conclusion Hyperbilirubinemia can damage the renal function of neonates, urinary microdose protein is a useful biomarker for early diagnosis.

关键词

新生儿/高胆红素血症/尿微量蛋白

Key words

neonate/hyperbilirubinemia/urinary microdose protein

分类

医药卫生

引用本文复制引用

王译,杜逸亭,徐若梅..尿微量蛋白在高胆红素血症新生儿中测定的意义[J].四川医学,2012,33(6):948-950,3.

四川医学

OACSTPCD

1004-0501

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