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奈达铂联合替吉奥治疗晚期食管癌的疗效观察

罗文娟 赵妍丽 吴文涛

四川医学2012,Vol.33Issue(6):968-970,3.
四川医学2012,Vol.33Issue(6):968-970,3.

奈达铂联合替吉奥治疗晚期食管癌的疗效观察

The observation of the effect of nedaplatin combined with gimeracil and oteracil porassium capsules in the treatment of advanced esophageal carcinoma

罗文娟 1赵妍丽 2吴文涛1

作者信息

  • 1. 绵阳404医院,四川绵阳621000
  • 2. 川北医学院附属医院,四川南充637000
  • 折叠

摘要

Abstract

Observing the clinical effect of curing advanced cancer of the esophagus by using nedaplatin joins gimeracil and oteracil porassium capsules. Methods 26 patients of advanced cancer of the esophagus take Nedaplatin for the 80 -100mg/m2 by joining Normal Saline 500ml with intravenous drip 2h, dl; and take gimeracil and oteracil porassium capsules for the 80mg/(m2.d) in two times ,preferably with a meal dl ~dl4. 21d for 1 period, then evaluate the curative effect at least two periods later. Results Each patients takes 4. 69 cycles on average, complete remission (CR) with 0 cases, part remission with (PR) 13 cases (50%), stable (NC)7 cases (26. 92% ), progress (PD) 6 patients (23.08% ), the total effective rate (RR) of 50% . The major adverse reaction is bone marrow depression . Conclusion The curative effect of curing advanced cancer of the esophagus by using nedaplatin joins gimeracil and oteracil porassium capsules is good, and the bad reaction is also smaller, it deserves to be clinical application.

关键词

食管癌/晚期/奈达铂/替吉奥

Key words

cancer of the esophagus/ late period/ nedaplatin/gimeracil and oteracil porassium capsules

分类

医药卫生

引用本文复制引用

罗文娟,赵妍丽,吴文涛..奈达铂联合替吉奥治疗晚期食管癌的疗效观察[J].四川医学,2012,33(6):968-970,3.

四川医学

OACSTPCD

1004-0501

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