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邻苯二甲酸二乙酯对蟾蜍蝌蚪红细胞微核的影响

张维建 石兴玲 张超

山东建筑大学学报Issue(1):25-27,35,4.
山东建筑大学学报Issue(1):25-27,35,4.

邻苯二甲酸二乙酯对蟾蜍蝌蚪红细胞微核的影响

Effects of diethyl phthalate on tadpole erythrocyte micronucleus

张维建 1石兴玲 2张超1

作者信息

  • 1. 山东建筑大学市政与环境工程学院,山东济南250101
  • 2. 山东建筑大学外语学院,山东济南250101
  • 折叠

摘要

Abstract

In order to explore toxicity induced by diethyl phthalate, toad tadpoles are exposed to different concentration of diethyl phthalate(the termina concentration are 0,1. 6,3. 2,6. 5,13,26μg/mL) to investigate the effects of diethyl phthalate on micronucleus(MNC) rate and nuclear abnormal cells. Results show that MNC and nuclear abnormal cells of toad tadpoles significantly increase with the increase of concentration of diethyl phthalate ( compared with the control group P < 0. 01) , and the difference is significant when concentration of diethyl phthalate is at 13μg/mL. Corrlation analysis shows that remarkable corrlation is found between the diethyl phthalate, MNC and nuclear abnormal cells and has a significant dose-effect relation. These results suggest that diethyl phthalate could induce the genotoxic effects on the toad tadpoles.

关键词

邻苯二甲酸二乙酯/蟾蜍蝌蚪/红细胞/微核率

Key words

phthalate/ toad tadpoles/ RBC/ micronucleus

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引用本文复制引用

张维建,石兴玲,张超..邻苯二甲酸二乙酯对蟾蜍蝌蚪红细胞微核的影响[J].山东建筑大学学报,2012,(1):25-27,35,4.

山东建筑大学学报

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