生物医学工程研究2012，Vol.31Issue(1)：31-33,39,4.
自发性高血压模型大鼠(SHR)与SD大鼠大脑中动脉的应力松弛特性
Middle Cerebral Artery Stress Relaxation Properties of the Spontaneously Hypertensive Rat Models(SHR) and the SD Rats
摘要
Abstract
To observe the stress relaxation properties of 5 month - old SD male rats and 5 month - old SHR male rat's middle cerebral arteries to find out the pathogenesis of hypertension and provide stress relaxation mechanical parameters.
Toke 10 middle cerebral arteries'samples of 5 months old normal SD male rats, and the 5 months old spontaneously hypertensive model rats (SHR),respectively,then installed them in electronic testing machine to do the stress relaxation test ,simulated ihe human bady temperature at (36.5 ?.5)?. The samples were Hone forcibly by 0.05%/s strain increases velocity, the time was set on 7 200 s,100 data were collected. The stress relaxation equations of the two groups' samples were calculated by using normalized analysis method.
The stress relaxation curve of the two groups'samples was changed by exponential relationship. The stress reduction of the middle cerebral arteries' samples of the SD rats at 7 200 s was greater than that of SH R rats', there was significant difference (P < 0.05). The middle cerebral arteries of the normal SD rats and SHR rats have different stress relaxation properties. The stress relaxation of middle cerebral arteries of the SHR rats have been changed.关键词
高血压/SHR大鼠/SD大鼠/大脑中动脉/应力松弛/对比分析Key words
Hypertension/SHR rats/SD rats/Middle cerebral artery/Stress relaxation/Contrast analysis分类
医药卫生引用本文复制引用
许东辉,李东原,李新颖..自发性高血压模型大鼠(SHR)与SD大鼠大脑中动脉的应力松弛特性[J].生物医学工程研究,2012,31(1):31-33,39,4.
