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肠易激综合征动物模型的复制与评价

刘艳霞 赵莹 刘蕾 刘俊康

实验动物与比较医学2012,Vol.32Issue(2):165-169,5.
实验动物与比较医学2012,Vol.32Issue(2):165-169,5.DOI:10.3969/j.issn.1674-5817.2012.02.019

肠易激综合征动物模型的复制与评价

Replication and Evaluation of Irritable Bowel Syndrome Animal Models

刘艳霞 1赵莹 1刘蕾 1刘俊康1

作者信息

  • 1. 第三军医大学药学院天然药物化学教研室,重庆 400038
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摘要

Abstract

The article summarized the replication methods and evaluation indicators of irritable bowel syndrome animal models. Combined with peripheral sensitization, relatively mild stress stimulus method was a relatively better choice which was to enhance the success rate of molding and consider animal welfare. Defecation frequency and character was the most intuitive and economic indicator in evaluation, but its specificity was poor. Intestinal sensitivity was the most specific indicator which depended on the detection of stress and correlated with clinical research.

关键词

肠易激综合征/动物模型/复制/评价指标

Key words

Irritable bowel syndrome/ Animal models/ Replication/ Evaluation indicators

分类

生物科学

引用本文复制引用

刘艳霞,赵莹,刘蕾,刘俊康..肠易激综合征动物模型的复制与评价[J].实验动物与比较医学,2012,32(2):165-169,5.

实验动物与比较医学

OACSTPCD

1674-5817

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