天然产物研究与开发2012,Vol.24Issue(6):848-855,8.
C7N氨基环醇家族的天然α-糖苷酶/淀粉酶抑制剂研究进展
Research Progress in Natural α-Glucosidase/Amylase Inhibitors Classified in the Family of C7N Aminocyclitols
摘要
Abstract
The C,N aminocyclitol family is a relatively new class of natural products that is increasingly gaining recognition due to their significant biomedical and agricultural uses. These secondary metabolites are exclusively produced by microorganisms,particularly soil bacteria of the order of Actinomycetes. Their chemical structures most commonly contain an unsaturated aminocyclitol moiety,valienamine,which is known to be responsible for their biological activities. Among the C7N aminocyclitol family,most members act as α-glucosidase/amylase inhibitors. This review covers the discovery, structure determinations, and biological properties of α-glucosidaae/amylase inhibitors classified in the family of C7N aminocyclitols,including the researches performed by the author of this article.关键词
C7N氨基环醇/α-糖苷酶/淀粉酶抑制剂/放线菌Key words
C7N aminocyclitol/α-ghicosidase/arnylase inhibitor/Actinomycetes分类
化学化工引用本文复制引用
耿鹏,白钢..C7N氨基环醇家族的天然α-糖苷酶/淀粉酶抑制剂研究进展[J].天然产物研究与开发,2012,24(6):848-855,8.基金项目
国家自然科学基金项目(30900015) (30900015)